CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000019022/1-968 -------------------------PVSSFTVNLLDTSTIHGDWGWLTYPAHGWDSINEV ENSMUSP00000030420/1-1004 MAPARARLSPALWVVTAAAAA-TCVSAGRGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV ENSRNOP00000017559/1-974 -------------------------------VNLLDTSTIHGDWGWLTYPAHGWDSINEV ENSP00000166244/1-1005 MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV XP_004850589.1/1-1005 MAPAWGRVSPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSISEV **************************.** ENSCPOP00000019022/1-968 DESFHPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE ENSMUSP00000030420/1-1004 DESFRPIHTYQVCNVMSPNQNNWLRTNWVPRDGARRVYAEIKFTLRDCNSIPGVLGTCKE ENSRNOP00000017559/1-974 DESFRPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSIPGVLGTCKE ENSP00000166244/1-1005 DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE XP_004850589.1/1-1005 DESFHPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE ****:*********************.***********************:********* ENSCPOP00000019022/1-968 TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRGVGPLSKRG ENSMUSP00000030420/1-1004 TFNLHYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRGVGPLSKRG ENSRNOP00000017559/1-974 TFNLHYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRGVGPLSKRG ENSP00000166244/1-1005 TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG XP_004850589.1/1-1005 TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRGVGPLSKRG ****:**********************************************.******** ENSCPOP00000019022/1-968 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER ENSMUSP00000030420/1-1004 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER ENSRNOP00000017559/1-974 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER ENSP00000166244/1-1005 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER XP_004850589.1/1-1005 FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER ************************************************************ ENSCPOP00000019022/1-968 DTPKMYCSAEGEWLVPIGKCVCSAGYEEQRDACVACELGFYKSAPGDQLCARCPLHSHSA ENSMUSP00000030420/1-1004 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACMACELGFYKSAPGDQLCARCPPHSHSA ENSRNOP00000017559/1-974 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACMACELGFYKSAPGDQLCARCPPHSHSA ENSP00000166244/1-1005 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA XP_004850589.1/1-1005 DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPLHSHSA ****************************:****:******************** ***** ENSCPOP00000019022/1-968 APAAQTCRCDLSYYRAALDPPSAACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI ENSMUSP00000030420/1-1004 TPAAQTCRCDLSYYRAALDPPSAACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI ENSRNOP00000017559/1-974 TPAAQTCRCDLSYYRAALDPPSAACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI ENSP00000166244/1-1005 APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI XP_004850589.1/1-1005 APAAQTCRCDLSYYRAALDPPSAACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI :****:*:**************:************************************* ENSCPOP00000019022/1-968 TYNAVCRRCPWTLSRCEACGSGTRFVPQQKSLVQASLLVANLLAHTNYSFWIEAVNGVSD ENSMUSP00000030420/1-1004 TYNAVCRRCPWALSHCEACGSGTRFVPQQTSLAQASLLVANLLAHMNYSFWIEAVNGVSN ENSRNOP00000017559/1-974 TYNAVCRRCPWALSHCEACGSGTRFVPQQTSLAQASLLVANLLAHMNYSFWIEAVNGVSN ENSP00000166244/1-1005 TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD XP_004850589.1/1-1005 TYNAMCRRCPWTLSRCEACGSGTRFVPQQKSLVQASLLVANLLAHTNYSFWIEAVNGVSD ****:******:**:**************.**.************ *************: ENSCPOP00000019022/1-968 LSPEPRQAAVVNITTNQAAPSQVVAIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK ENSMUSP00000030420/1-1004 LSPEPRSAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK ENSRNOP00000017559/1-974 LSPEPRNAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK ENSP00000166244/1-1005 LSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK XP_004850589.1/1-1005 LSPEPRRAAVVNITTNQAAPSQVVAIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK ****** *****************.*********************************** ENSCPOP00000019022/1-968 DKETQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPREVFSF ENSMUSP00000030420/1-1004 DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT ENSRNOP00000017559/1-974 DKEMQSYSTLKAVTTRATVSGLKPGTRYMFQVRARTSAGCGRFSQAMEVETGKPRPRYDT ENSP00000166244/1-1005 DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT XP_004850589.1/1-1005 DKETQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT *** ************************:************************** :. ENSCPOP00000019022/1-968 PTVSSRLLPLPW-SLGVLISLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQSGQ----- ENSMUSP00000030420/1-1004 RTIV-------WICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPV ENSRNOP00000017559/1-974 RTIV-------WICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPV ENSP00000166244/1-1005 RTIV-------WICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPV XP_004850589.1/1-1005 RTIV-------WICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQSGQAPPPV *: * .* :: .********************************.** ENSCPOP00000019022/1-968 --------GKLPEPQFYAEPHNYEEPGRAGHGFTREIEASRIHIEKIIGSGCPGESGEVC ENSMUSP00000030420/1-1004 FLPLNHPPGKFPETQFSAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGS---GESGEVC ENSRNOP00000017559/1-974 FLPLNHPPGKLPETQFSAEPHNYEEPGRAGRSFTREIEASRIHIEKIIGS---GESGEVC ENSP00000166244/1-1005 FLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGS---GDSGEVC XP_004850589.1/1-1005 FLPLHHPPGKLPEPQFYAEPHTYEEPGRAGRGFTREIEASRIHIEKIIGS---GESGEVC **:**.** ****.********:.****************** *:***** ENSCPOP00000019022/1-968 YGRLRVPGQQDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAM ENSMUSP00000030420/1-1004 YGRLQVPGQRDVPVAIKALKAGYTERQRQDFLSEAAIMGQFDHPNIIRLEGVVTRGRLAM ENSRNOP00000017559/1-974 YGRLQVPGQRDVPVAIKALKAGYTERQRQDFLREAAIMGQFDHPNIIRLEGVVTRGRLAM ENSP00000166244/1-1005 YGRLRVPGQRDVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAM XP_004850589.1/1-1005 YGRLRVPGQLDMPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAM ****:**** *:****************:*** **:************************ ENSCPOP00000019022/1-968 IVTEYMENGSLDAFLRIHDGQFTIMQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVDG ENSMUSP00000030420/1-1004 IVTEYMENGSLDAFLRTHDGQFTIVQLVGMLRGVGAGMRYLSDLGYIHRDLAARNVLVDG ENSRNOP00000017559/1-974 IVTEYMENGSLDAFLRTHDGQFTILQLVGMLKGVGAGMRYLSDLGYIHRDLAARNILVDG ENSP00000166244/1-1005 IVTEYMENGSLDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDS XP_004850589.1/1-1005 IVTEYMENGSLDAFLRIHDGQFTIMQLVGMLRGVGAGMRYLSDLGYIHRDLAARNILVDG ************:*** *******:******:**************:********:***. ENSCPOP00000019022/1-968 NLVCKVSDFGLSRVLEDDPNAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWE ENSMUSP00000030420/1-1004 RLVCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWE ENSRNOP00000017559/1-974 RLVCKVSDFGLSRALEDDPEAAYTTAGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWE ENSP00000166244/1-1005 NLVCKVSDFGLSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWE XP_004850589.1/1-1005 NLVCKVSDFGLSRVLEDDPNAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWE .************.*****:*****:********************************** ENSCPOP00000019022/1-968 VLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRTQRPRFSHIVS ENSMUSP00000030420/1-1004 VLAYGERPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFAHVVS ENSRNOP00000017559/1-974 VLAYGERPYWNMTNQDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSHVVS ENSP00000166244/1-1005 VLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVS XP_004850589.1/1-1005 VLAYGERPYWNMTNRDVISSVEEGYRLPAPMGCPRALHQLMLDCWHKDRAQRPRFSHIVS **************:*******************:**************:*****:::** ENSCPOP00000019022/1-968 VLDALIRSPESLRATATAGRCLAPTPAPA-----QNKPGLSPLPESDWLDSIRMGRYRDH ENSMUSP00000030420/1-1004 VLDALVHSPESLRATATVSRCPPPAFARSCFDLRAGGSGNGDLTVGDWLDSIRMGRYRDH ENSRNOP00000017559/1-974 VLEALVHSPESLRATATVSRCPAPAFARSCFDLRAGGNGNGDLTVGDWLDSIRMGRYRDH ENSP00000166244/1-1005 VLDALIRSPESLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDH XP_004850589.1/1-1005 VLDALVRSPESLRATATTGRCPPPAFARSCFDLRGGGGGGGGLTVGDWLDSIRMGRYRDH **:**::**********..** .*: . : . * . *. .************** ENSCPOP00000019022/1-968 FAAGGYSSLGMVLRMDAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPR--- ENSMUSP00000030420/1-1004 FAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLSSTQGPRRHL ENSRNOP00000017559/1-974 FAAGGYSSLGMVLHMNAQDVRALGITLMGHQKKILGSIQTMRSQLSCTQGPRRHL ENSP00000166244/1-1005 FAAGGYSSLGMVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL XP_004850589.1/1-1005 FAAGGYSSLGMVLRMDAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL *************:*:**************************:**:.*****