CLUSTAL W(1.81) multiple sequence alignment ENSMUSP00000101535/1-1594 MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHTFSEN ENSRNOP00000059351/1-1592 MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHTFSEN ENSP00000247087/1-1603 MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSEN ENSCPOP00000016325/1-1603 MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPAPRPLLPTRPPASPPDKAFSTHTFSEN XP_004850781.1/1-1600 MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPAPRPLLPTRPPASPPDKAFSTHTFSEN *********************************:*********************:**** ENSMUSP00000101535/1-1594 PRPPPRRDPSSRRPPVLAKGDDLLPPRAARPVSQAHCPSPAPD-NSSLRHWDNGRVNLRP ENSRNOP00000059351/1-1592 PRPPPRRDPSSRRPPVLAKGDDLLPPRAARPVSQAHCPTPAPD-NNSLRHWDNGRVNLHP ENSP00000247087/1-1603 PRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRP ENSCPOP00000016325/1-1603 PRPPPRRDPSTRRPPVLPKGDDPLPPRAARPVSQARCPIPAGDRSSSRRLWDNGRVNLRP XP_004850781.1/1-1600 PRPPPRRDPSTRRPPVLPKGDDPLPPRAARPISQARCPIPAGD-SSSRCHWDNGRVNLHP **********:******.**** ********:***:** *. * ..* ********:* ENSMUSP00000101535/1-1594 VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP ENSRNOP00000059351/1-1592 VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP ENSP00000247087/1-1603 VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP ENSCPOP00000016325/1-1603 VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP XP_004850781.1/1-1600 VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP ************************************************************ ENSMUSP00000101535/1-1594 EERANPHTKSERPSHPLYEPEPEPRDSPQPGQGHGPGAAATATGLPPEPEPDGPDYSELA ENSRNOP00000059351/1-1592 EERATPHAKPERPNHPLYEPEPEPRDSPQPGQGHGPGATATATGLPPEPEPDGPDYPELA ENSP00000247087/1-1603 EERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELA ENSCPOP00000016325/1-1603 EERATPHAKSERPSHPLYEPEPEPRDSPQPGQGRSPGATAAATGLPPEPEPDGPDYSELA XP_004850781.1/1-1600 EERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDGPDYSELA ****.**:*.***.*******************:.***:*:***********..**.*** ENSMUSP00000101535/1-1594 DADILSELASLTCPEAQLLEAQALEPPSPQPEPQLLDPQPRFLDPQALEPLGEGLELPPL ENSRNOP00000059351/1-1592 DADILSELASLTCPEAQLLEAQALEPPSPQPEPQLLDPQPRFLDPQALEPLGEGLELPPL ENSP00000247087/1-1603 DADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPL ENSCPOP00000016325/1-1603 EADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPL XP_004850781.1/1-1600 EADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPL :****************************:***********************.****** ENSMUSP00000101535/1-1594 QPLADPLGLPSLTLQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQSLGHCQLA ENSRNOP00000059351/1-1592 QPLADPLGLPSLTLQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQSLGHCQLA ENSP00000247087/1-1603 QPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLA ENSCPOP00000016325/1-1603 QPLADPLGLPSLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLESQQPLGHCPLA XP_004850781.1/1-1600 QPLADPLGLPSLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGHRLEPQQPLGHCPLA **********.*:********************************:***.**.**** ** ENSMUSP00000101535/1-1594 EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADSGPEGRLLPLPMPT ENSRNOP00000059351/1-1592 EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKVDSGPEGRLLPLPMPT ENSP00000247087/1-1603 EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPT ENSCPOP00000016325/1-1603 EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPT XP_004850781.1/1-1600 EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPT ********************************************.*:************* ENSMUSP00000101535/1-1594 GLAAALAEPPP-LPPPPPPTLSGPG--PVPELEPESSQTPMVPTRKGKCRGVRRMVVKMA ENSRNOP00000059351/1-1592 GLAAALAEPPPLPPPPPPPALSG----PVPELEPESSQTPMVPTRKGKCRGVRRMVVKMA ENSP00000247087/1-1603 GLVAALAEPPP-PPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMA ENSCPOP00000016325/1-1603 GLAAVLAEPPP-PPPPPPPALPGPGPVPVPELEPESSQTPVAPARKGKCRGVRRMVVKMA XP_004850781.1/1-1600 GLGAVLAEPPP-PPPPLPPVLPGPG--PVQELEPESSQTPVVPARKGKCRGVRRMVVKMA ** *.****** *** **.*.* .* **:*******:..:**************** ENSMUSP00000101535/1-1594 KIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSSEPTPLLKMKNNGRNVVVVFPPGEM ENSRNOP00000059351/1-1592 KIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSSEPTPLLKMKNNGRNVVVVFPPGEM ENSP00000247087/1-1603 KIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEM ENSCPOP00000016325/1-1603 KIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEM XP_004850781.1/1-1600 KIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEM ***********************************:************************ ENSMUSP00000101535/1-1594 PIILKRKRGRPPKNLLLGPGKPKEPTVVAAEAATVTAATMAMPEVKKRRRRKQKLASPQP ENSRNOP00000059351/1-1592 PIILKRKRGRPPKNLLLGPGKPKEPTVVAAEAAAVTAATMAMPEVKKRRRRKQKLASPQP ENSP00000247087/1-1603 PIILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAATMAMPEVKKRRRRKQKLASPQP ENSCPOP00000016325/1-1603 PIILKRKRGRPPKNLLLGPGKPKEPTVVATEAATITATTMAIPEVKKRRRRKQKLASPQP XP_004850781.1/1-1600 PIILKRKRGRPPKNLLLGPGKPKEPAVVATEAATVAAATMAIPEVKKRRRRKQKLASPQP *************************:***:***:::*:***:****************** ENSMUSP00000101535/1-1594 SYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISQFL ENSRNOP00000059351/1-1592 SYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISQFL ENSP00000247087/1-1603 SYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISHFL ENSCPOP00000016325/1-1603 SYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISHFL XP_004850781.1/1-1600 SYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISHFL *********************************************************:** ENSMUSP00000101535/1-1594 HRVQGFRRRGGKTGGFGGRGGGHAAKAARCSFSDFFEGIGKKKKVVAVAAPGLVGPGLTE ENSRNOP00000059351/1-1592 HRVQGFRRRGGKTGGFGGRGGGHAAKAARCSFSDFFEGIGKKKKVVAVAATGVVGPGLTE ENSP00000247087/1-1603 HRVQGFRRRGGKAGGFGGRGGGHAAKSARCSFSDFFEGIGKKKKVVAVAAAGVGGPGLTE ENSCPOP00000016325/1-1603 HRVQGFRRRGGKTGGFGGRGGGHAAKAARCSFSDFFEGIGKKKKVVAVAAAEVGGPGLTE XP_004850781.1/1-1600 HRVQGFRRRGGKAGGFGGRGGGHAAKAARCSFSDFFEGIGKKKKVVTVAAAGVGGPGLTE ************:*************:*******************:***. : ****** ENSMUSP00000101535/1-1594 LGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWVGDKGGGWAPH ENSRNOP00000059351/1-1592 LGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPH ENSP00000247087/1-1603 LGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPH ENSCPOP00000016325/1-1603 LGHPRKRGRGEVDALTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPH XP_004850781.1/1-1600 LGHPRKRGRGEVDALTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGVEWPGDKSGGWAPH **************:*******************************.** ***.****** ENSMUSP00000101535/1-1594 HGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYA-GAPSGQTELSQERQNLFTGY ENSRNOP00000059351/1-1592 HGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYA-GAPSGQTELSQERQNLFTGY ENSP00000247087/1-1603 HGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQERQNLFTGY ENSCPOP00000016325/1-1603 HGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGTPSGQTELSQERQNLFTGY XP_004850781.1/1-1600 HGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTATPSGQTELSQERQNLFTGY **************************************: .:****************** ENSMUSP00000101535/1-1594 FRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPSSALPAQRGLATFPSRGAKASPVA ENSRNOP00000059351/1-1592 FRSLLDSDDSSDLLDFALSASRPESRKASGNYAGPPSSALPAQRGLATFPSRGAKGSPVA ENSP00000247087/1-1603 FRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVA ENSCPOP00000016325/1-1603 FRSLLDSDDSSDLLDFALSASRAESRKASGTYTGPPTTALPAQRGLATFPSRGAKASPVA XP_004850781.1/1-1600 FRSLLDSDDSSDLLDFALSASRPESRKASGTYTGPPTSALPTQRGLATFPSRGAKASPVA **********************.*******.*:***::***:*************.**** ENSMUSP00000101535/1-1594 VGSSGAGADPSFQPVLPSRQTFPPGRATSYGITPATSDCRAAETFPKLAPPPSAVARSPT ENSRNOP00000059351/1-1592 VGNSGAGTDPSFQPVLPSRQTFPPGRATSYGITPATSDCRAAETFPKLAPPPSAVARSPT ENSP00000247087/1-1603 VGSSGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPT ENSCPOP00000016325/1-1603 VGNSGTGADPSFQPVLPTRQTFPPGRAGSYGLTPATSDCRAAETFPKLAPPPSAVARSPT XP_004850781.1/1-1600 VGSSGAGADPSFQPVLPTRQTFPPGRATSYGITPATSDCRAAETFPKLAPPPSAVARSPT **.**:*:********.:********* ***:***:************.*****:***** ENSMUSP00000101535/1-1594 THPPANTYPPQYGGYGAGQSVFASAKPFSGQDCANSKDCSFAYGSGNSLPASPSSAHSAG ENSRNOP00000059351/1-1592 THPPANTYPPQYGGYGAGQSVFAPAKPFSGQDCANSKDCSFAYGSGNSLPASPSSAHSAG ENSP00000247087/1-1603 THPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAG ENSCPOP00000016325/1-1603 THPPTNTYPPQYGGYGAGQSVFAPAKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAG XP_004850781.1/1-1600 THPPTNTYPPQYGGYGAGQSVFAPAKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAG ****:*** **************.:***:******************************* ENSMUSP00000101535/1-1594 YAPPPTGGPCLPPSKASFFNSSEGGPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTA--- ENSRNOP00000059351/1-1592 YAPPPTGGPCLPPSKASFFNSSEGGPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTA--- ENSP00000247087/1-1603 YAPPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASAT ENSCPOP00000016325/1-1603 YAPPPTGGPCLPPNKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASAT XP_004850781.1/1-1600 YAPPPTGGPCLPPSKASFFNSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASAT *************.*****.****.******************************** ENSMUSP00000101535/1-1594 SAASVASSSSSSFQPSPENCRQFVGASQWPFRQGYGGLDWASEAFSQLYNPNFDCHGSEP ENSRNOP00000059351/1-1592 SAASAASSSSSSFQPSPENCRQFVGASQWPFRQGYGGLDWASEAFSQLYNPNFDCHVSEP ENSP00000247087/1-1603 SAASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEP ENSCPOP00000016325/1-1603 SAASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEP XP_004850781.1/1-1600 SAASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEP ****.******************.***************************.**** *** ENSMUSP00000101535/1-1594 NVILDISNYTPQKVKQQTAVSETFSESSSDSTQFSQPVGGGGFRRANSEASSSEGQSSLS ENSRNOP00000059351/1-1592 NVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPV-GGGFRRANSEASSSEGQSSLS ENSP00000247087/1-1603 NVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLS ENSCPOP00000016325/1-1603 NVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLS XP_004850781.1/1-1600 NVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVSGGGFRRANSEASSSEGQSSLS **********************************.*** ********************* ENSMUSP00000101535/1-1594 SLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFSTSTSATASG ENSRNOP00000059351/1-1592 SLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFSTSTSATASG ENSP00000247087/1-1603 SLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASG ENSCPOP00000016325/1-1603 SLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFETSHLGFSTSASAAASG XP_004850781.1/1-1600 SLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFSTSASAAASG ********************************************:*****.**:**:*** ENSMUSP00000101535/1-1594 YPSKRSTGPRQPRGGRGSGACSAKKERGGTAAKAKFIPKPQPVNPLFQDSPDLGLDYYSG ENSRNOP00000059351/1-1592 YPSKRSTGPRQPRGGRGSGACSAKKERGGTAAKAKFIPKPQPVNPLFQDSPDLGLDYYSG ENSP00000247087/1-1603 YPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSG ENSCPOP00000016325/1-1603 YPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSG XP_004850781.1/1-1600 YPSKRSTGPRQPRGGRGSGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSG *****************.***********:****************************** ENSMUSP00000101535/1-1594 DSSMSPLPSQSRAFGVGERDPCDFMGPYSMNPSTPSDGTFGQGFHCDSPSLGAAELDGKH ENSRNOP00000059351/1-1592 DSSMSPLPSQSRAFGVGERDPCDFMGPYSMNPSTPSDGTFGQGFHCDSPSLGAPDLDSKH ENSP00000247087/1-1603 DSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKH ENSCPOP00000016325/1-1603 DSSMSPLPSQSRAFSVGERDPCDFMGPYSMNPSTPSDGTFGQGFHCDSPSLGAPDLDGKH XP_004850781.1/1-1600 DSSMSPLPSQSRAFSVGERDPCDFMGPYSMNPSTPSDGTFGQGFHCDSPSLGAPDLDGKH **************.*********:****************************.:**.** ENSMUSP00000101535/1-1594 FPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPSKLTACEPLKHGLQGASLSH--A ENSRNOP00000059351/1-1592 FPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPSKLTACEPLKHGLQGASLSH--A ENSP00000247087/1-1603 FPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAA ENSCPOP00000016325/1-1603 FPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHVAA XP_004850781.1/1-1600 FPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHTAA *************************************:**:**************.* * ENSMUSP00000101535/1-1594 AQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGSGLLADFLGRTEAVC ENSRNOP00000059351/1-1592 AQAHLSCRDLPLGQPHYESPSCKGTAYWYPPGSAARSPPYEGKVGSGLLADFLGRTEAVC ENSP00000247087/1-1603 AQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAAC ENSCPOP00000016325/1-1603 AQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEATC XP_004850781.1/1-1600 AQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAAC *****************:***************************:************.* ENSMUSP00000101535/1-1594 LSAPHLASPPATPKADKEPLEMARPPGPPRGPAAATAGYGCPLLSDLTLSPVPRDSLLPL ENSRNOP00000059351/1-1592 LSAPHLASPPATPKADKEPLEMTRPPGPPRGPAAATAGYGCPLLSDLTLSPVPRDSLLPL ENSP00000247087/1-1603 LSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPL ENSCPOP00000016325/1-1603 LSAPHLASPPATPKADKEPLEMARPPGPPRGPAAVAAGYGCPLLSDLTLSPVPRDSLLPL XP_004850781.1/1-1600 LTAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPL *:********************:***********.:************************ ENSMUSP00000101535/1-1594 QDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL ENSRNOP00000059351/1-1592 QDTAYRYPGFMPQTHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL ENSP00000247087/1-1603 QDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL ENSCPOP00000016325/1-1603 QDTAYRYPGFIPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL XP_004850781.1/1-1600 QDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL **********:**:******************************