CLUSTAL W(1.81) multiple sequence alignment ENSCPOP00000014398/1-878 PLWSRHPLCKRSGCRWRIKQLRSDYERRENAMKRQSERDSSPSGRGSSSSAKRPRERERE XP_004834221.1/1-890 -------------------------------MKRQSERDSSPSGRGSSSSAKRPRERERE ENSP00000313890/1-890 -------------------------------MKRQSERDSSPSGRGSSSSAKRPRERERE ENSMUSP00000059330/1-887 -------------------------------MKRQSERDSSPSGRGSSSSAKRPRERERE ENSRNOP00000018994/1-887 -------------------------------MKRQNERDSSPSGRGSSSSAKRPRERERE ****.************************ ENSCPOP00000014398/1-878 AEAGGRRAVHKASGGAKHPVPARARDKPRGSGGGGGGHRDGRGAGDANHRVSSGRSSGSG XP_004834221.1/1-890 AEVGGRRAVHKASGGAKHPVQARARDKPRGTGGGGGGHRDGRGAGDANHRAGSGRSSGSG ENSP00000313890/1-890 AEAGGRRAAHKASGGAKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRASSGRSSGSG ENSMUSP00000059330/1-887 AEAGGRRAAHKASGGTKHPVPARARDKPRGSG-GGGGHRDGRAAGDANHRASGGRSSGA- ENSRNOP00000018994/1-887 AEAGGRRAAHKASGGTKHPVPARARDKPRGSG-GGGGHRDGRAAGDANHRASSGRSSGA- **.*****.******:**** *********:* *********.:******...*****: ENSCPOP00000014398/1-878 AGGGGRGGKASGDPGASGASPRASPLP---------PAGPG-SAGVPEYKTLLISSLSPA XP_004834221.1/1-890 AGGGGRGGKASGDPGASGASPRASPLPPPPPPPGAEPAGPG-SAAVPEYKTLLISSLSPA ENSP00000313890/1-890 AGGGGRGGKASGDPGASGMSPRASPLPPPPPPPGAEPACPGSSAAAPEYKTLLISSLSPA ENSMUSP00000059330/1-887 PGGGGRTGKASGDPGAGGASPRASPLPPPPPPPGAEPAGPG-STAAPEYKTLLISSLSPA ENSRNOP00000018994/1-887 PGGGGRTGKASGDPGAGGASPRASPLPPPPPPPGAEPAGPG-TTAAPEYKTLLISSLSPA .***** *********.* ******** ** ** ::..************** ENSCPOP00000014398/1-878 LPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYD XP_004834221.1/1-890 LPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYD ENSP00000313890/1-890 LPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYD ENSMUSP00000059330/1-887 LPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYD ENSRNOP00000018994/1-887 LPAEHLEDRLFHQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYD ************************************************************ ENSCPOP00000014398/1-878 RPLKVEPVYLR------RRHHAAPGASCASRPARLPAAA--------------RRVPVQA XP_004834221.1/1-890 RPLKVEPVYLRGGGGGSSRRSSSSSAAATTPPPGPPAPADPLGYLPLHGGYQYKQRSLSP ENSP00000313890/1-890 RPLKVEPVYLR-GGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSP ENSMUSP00000059330/1-887 RPLKVEPVYLR--GGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSP ENSRNOP00000018994/1-887 RPLKVEPVYLR--GGGSSRRSSSSSAAASTPPPGPPTPADPLGYLPLHGGYQYKQRSLSP *********** *: ::..*:.:: *. *:.* :: .:.. ENSCPOP00000014398/1-878 ALAVPSRCPTL----------AGAPRPLGLSRERALDYYGLYDDRGRPYGYPAVCEEDLM XP_004834221.1/1-890 VAAPPLREPRARHAAAAFALDAAAAAAAGLSRERALDYYGLYDDRGRPYSYPAVCEEDLM ENSP00000313890/1-890 VAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLM ENSMUSP00000059330/1-887 VAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYGYQAVCEEDLM ENSRNOP00000018994/1-887 VAAPPLREPRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYSYQAVCEEDLM . * * * * *.*. . *********************.* ******** ENSCPOP00000014398/1-878 PEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARG----YAFLKFQNLD XP_004834221.1/1-890 PEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLD ENSP00000313890/1-890 PEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLD ENSMUSP00000059330/1-887 PEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLD ENSRNOP00000018994/1-887 PEDDQRATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLD ********************************************** ********** ENSCPOP00000014398/1-878 MAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTID XP_004834221.1/1-890 MAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTID ENSP00000313890/1-890 MAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTID ENSMUSP00000059330/1-887 MAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTID ENSRNOP00000018994/1-887 MAHRAKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTID ************************************************************ ENSCPOP00000014398/1-878 HVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPV XP_004834221.1/1-890 HVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEESRYPQQYQPSPLPV ENSP00000313890/1-890 HVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPV ENSMUSP00000059330/1-887 HVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPV ENSRNOP00000018994/1-887 HVKGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPV **********************************************:************* ENSCPOP00000014398/1-878 HYELLTDGYTRHRTLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLESYS XP_004834221.1/1-890 HYELLTDGYTRHRTLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSPAKSSDRRNSLEGYS ENSP00000313890/1-890 HYELLTDGYTRHRNLDADL-VRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGYS ENSMUSP00000059330/1-887 HYELLTDGYTRHRNLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSLSKSSDRRNSLEGYS ENSRNOP00000018994/1-887 HYELLTDGYTRHRNLDADLRVRDRTPPHLLYSDRDRTFLEGDWTSLSKSSDRRNSLEGYS *************.***** ************************* :**********.** ENSCPOP00000014398/1-878 RSVRSRSGERWGGDGDRGMPKPWEDRRKRRSLSSDRGRTTHSPYEERSRTKGGGQQADRG XP_004834221.1/1-890 RSVRSRSGERWGGEGDRGMPKPWEDRRKRRSLSSDRGRTTHSPYEERSRTKGGGQQSDRS ENSP00000313890/1-890 RSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQSERG ENSMUSP00000059330/1-887 RSVRSRSGERWGGDGDRSIAKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGGGQQSERG ENSRNOP00000018994/1-887 RSVRSRSGERWGADGDRSIAKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGGGQQSERG ************.:***.:.****:***************************.***::*. ENSCPOP00000014398/1-878 CDRTPERSRKENHSGEGTKESG-NSLSNSRHGAEER-------KAPDCSHGKKVRESERN XP_004834221.1/1-890 SDRTPERSRKENHSGEGTKESGSNSLSNSRHGAEERSHHHHHHEAPDSSHGKK-RESERN ENSP00000313890/1-890 SDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKARDSERN ENSMUSP00000059330/1-887 SDRTPERSRKENHSSEGTKESGSNSLSNSRHGAEERSHHHHHHEAPDSSHGKKTRESERN ENSRNOP00000018994/1-887 SDRTPERSRKENHSSEGTKESGSNSLSNSRHSAEERSHHHHHHEAPDSSHGKKTRESERN .*************.******. ********.**** :*.*.***** *:**** ENSCPOP00000014398/1-878 HRTTEVEPKPLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVI XP_004834221.1/1-890 HRTTEAEPKPLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVI ENSP00000313890/1-890 HRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVI ENSMUSP00000059330/1-887 HRTTEAEPKTLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVI ENSRNOP00000018994/1-887 HRTTEAEPKTLEEPKHETKKLKTLSEYAQTLQLGWNGLLVLKNSCFPTSMHILEGDQGVI *****.***.************.************************************* ENSCPOP00000014398/1-878 SGLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQAAPSGPGTE XP_004834221.1/1-890 SGLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQAAPSGPGTE ENSP00000313890/1-890 SSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQATPSGLGTE ENSMUSP00000059330/1-887 SGLLKDHPSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLAIQSTPSGPGAE ENSRNOP00000018994/1-887 SGLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLAIQSTPSGPGAE *.*****.***************************************** *::*** *:* ENSCPOP00000014398/1-878 VMATVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDLTGMLYAFPPCDFSQQYLQ XP_004834221.1/1-890 AMATVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDITGMLYAFPPCDFSQQYLQ ENSP00000313890/1-890 GMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYAFPPCDFSQQYLQ ENSMUSP00000059330/1-887 GMPVVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDNTGMLYAFPPCDFSQQYLQ ENSRNOP00000018994/1-887 GMPMVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDSTGMLYAFPPCDFSQQYLQ *. ************************************* ****************** ENSCPOP00000014398/1-878 SALRTLGKLEEEHMVIVIINLVQSKFLDGG XP_004834221.1/1-890 SALRTLGKLEEEHMVIVIVR-------DTA ENSP00000313890/1-890 SALRTLGKLEEEHMVIVIVR-------DTA ENSMUSP00000059330/1-887 SALRTLGKLEEEHMVIVIVR-------DTA ENSRNOP00000018994/1-887 SALRTLGKLEEEHMVIVIVR-------DAA ******************:. * .